Acepromazine – Veterinary Sedative & Tranquilizer for Safe Animal Care
What is Acepromazine?
Acepromazine maleate is a phenothiazine derivative used as a tranquilizer and sedative in veterinary medicine. It is available in injectable solutions and oral tablets, making it versatile for different clinical situations. Veterinarians prescribe it for horses, dogs, cats, and other animals to reduce anxiety, provide chemical restraint, and prepare animals for anesthesia.
Key Benefits
- Sedation & Tranquility: Reduces anxiety and calms animals during stressful events.
- Pre‑Anesthetic Use: Helps prepare animals for surgery by lowering reactivity.
- Chemical Restraint: Facilitates safe handling of nervous or aggressive animals.
- Anti‑Nausea Effect: Useful for pets prone to motion sickness.
- Versatile Administration: Available in tablets and injectable forms.
Composition & Presentation
- Active Ingredient: Acepromazine maleate
- Forms:
- Tablets (10 mg, 25 mg)
- Injectable solution (10 mg/mL, 50 mL vials)
- Brands: PromAce®, VetOne, Aceprotabs
How Acepromazine Works
Acepromazine acts on the central nervous system, producing sedation by blocking dopamine receptors. This results in:
- Reduced anxiety and agitation
- Muscle relaxation
- Lowered responsiveness to external stimuli
Unlike analgesics, acepromazine does not relieve pain directly but is often combined with other medications for comprehensive care.
Administration Guidelines
- Injectable: Intramuscular, intravenous, or subcutaneous use.
- Oral Tablets: Administered 45–60 minutes before procedures or travel.
- Dosage: Determined by a veterinarian based on species, weight, and condition.
Important: Never administer without veterinary supervision. Incorrect dosing can cause serious side effects.
Safety & Precautions
- Use only under veterinary guidance.
- Not recommended for animals with cardiovascular issues.
- Avoid use in breeding stallions due to risk of penile prolapse.
- Monitor for side effects such as hypotension or lethargy.
Why Choose Acepromazine?
- Trusted for Decades: Widely used in veterinary practice.
- Multiple Forms: Tablets and injections for flexible use.
- Global Availability: Shipped to major equestrian and pet care regions worldwide.
- Cost‑Effective: Provides reliable sedation at affordable prices.
Customer Testimonials
Owners and trainers report:
- Calmer horses during transport and veterinary procedures.
- Reduced anxiety in dogs and cats during grooming or travel.
- Safe restraint for handling nervous or aggressive animals.
Frequently Asked Questions
Q: Does Acepromazine relieve pain? A: No, it is a sedative. Pain relief requires additional medications.
Q: How long does it last? A: Effects typically last 6–8 hours depending on dosage and species.
Q: Is it safe for all animals? A: It must be prescribed by a veterinarian; certain animals may have contraindications.
Global Reach
Acepromazine is available for shipping to USA, UK, Canada, Australia, Germany, France, Switzerland, Spain, Portugal, and other European countries, ensuring accessibility for veterinarians and animal owners worldwide.
Buy Acepromazine Online
Acepromazine Maleate Injection is used for sedation, tranquilization and as a pre-anesthetic agent in horses, dogs and cats. Each ml contains 10 mg Acepromazine Maleate. Can be used as an aid in controlling animals during examination, treatment and minor surgical procedures. Maleate has a depressant effect on the central nervous system and therefore causes sedation, muscular relaxation and a reduction in spontaneous activity. It acts rapidly, exerting a prompt and pronounced calming effect. It is an effective pre-anesthetic agent and lowers the dosage requirement of general anesthetics.
Acepromazine Maleate Injection may be given intravenously, intramuscularly or subcutaneously. The general dosage of Maleate Injection for horses is 2-4 mg per 100 lbs body weight; dogs 0.25-0.5 mg per lb body weight; for cats 0.5-1.0 mg per lb body weight.
Not for use in animals hypersensitive (allergic) to it or other phenothiazines. Use with caution in debilitated or geriatric animals and those with liver or heart disease. Do not use in pregnant or lactating animals (female animals nursing their young) unless benefits outweigh the risks. Do not use in animals with hypovolemia (low blood volume), anemia, or shock. Do not use in animals with tetanus or strychnine toxicity. May cause seizures. Do not use with animals known to have seizures or are having medical procedures known to cause seizures (e.g., myelograms). When used to aid in restraint, the sedative effect can be overridden and the animal may bite or jump unexpectedly. Promace is an inappropriate medication for the treatment of aggression since it can make aggressive animals less predictable, and can interfere with training. Causes low blood pressure and inability to maintain proper body temperature. ACEPROMAZINE ACEPROMAZINE ACEPROMAZINE ACEPROMAZINE
Does not provide any pain relief. Giant breeds, greyhounds, and boxers may be more sensitive to its effects; terriers may be less sensitive. Effects may last 6-8 hours, and results may not be consistent when given orally. Consult with your veterinarian regarding the physical examinations and laboratory testing necessary prior to and during treatment with promace.
Drug, Food, and Test Interactions:
Consult your veterinarian before using promace with vitamins, supplements, atropine, central nervous system (CNS) depressant drugs (such as barbiturates, narcotics, and antidepressants), organophosphate dewormer or insecticide, kaopectate, Pepto-Bismal, other antidiarrheal mixures, antacids, propranolol, and epinephrine. May have an adverse heart reaction if used with quinidine. Phenytoin levels and procaine activity may be increased if used with promace.
Acepromazine is a trusted veterinary sedative and tranquilizer that ensures safe handling, reduced anxiety, and effective pre‑anesthetic preparation. With its proven track record, multiple forms, and global availability, it remains a cornerstone in veterinary care for horses, dogs, and cats.


















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